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Stocks / Health Care · Pharmaceuticals

SDGR

Schrodinger SDGR

Health Care · Pharmaceuticals
$26.19−3.50% dayMon Nov 2 close

Outside our quality screen, so we don’t track its dips. It’s 20% below its 52-week high.

Outside our quality screen. No fair value estimate for now: its free cash flow is negative.

Outside our quality screenReports Nov 4
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Fair value est.
n/a
Market Value
$26.02price +1%
Off 52-wk high
−20%
Risk vs market
Highbeta 1.76

52-week range 70% of the way from its 52-week low to its high

Low $11.07High $32.60

Price $26.19Market Value $26.02

3 bullish · 5 bearish See why

Covered for reference — doesn’t pass our quality screen (market cap $2.0B, under our $20B floor; no positive free cash flow; ROE under 12% and ROIC under 10%). We show its price, Market Value and DCF, but it never appears in Dips, Top Picks or reversal signals. The screen

Priced in

How much growth the market assumed at the 52-week high, the low and today (a reverse DCF).

At the low ($11.07, Mar 30) about 29%. The last 3 years delivered 12%/yr (revenue).

  • 52-wk highn/a
  • 52-wk low$11.07+29%
  • Nown/a

Dashed line: what the last 3 years delivered, 12%/yr (revenue)

HighLowNow
Price$32.60Oct 5$11.07Mar 30$26.19
Implied growthn/a+29%n/a
P/FCF—65.3×—

What this means: the higher the implied growth, the more the price already counts on. If today's number sits well below what the business has delivered, the market expects less than its track record.

How it’s computed

Reverse DCF: the same 10-year free-cash-flow model as our fair value estimate (9.5% discount rate, growth for years 1–5 fading to 3% by year 10, 3% after), solved for the growth that makes it equal the market value at each price. For the high and the low we use only the filings that were public on that day, so nothing from a later report leaks back. Market value = that close × diluted shares. P/E = market value / 12-month net income; Price / FCF = market value / 12-month free cash flow; EV / Sales = (market value + debt − cash) / 12-month revenue. Hidden when the share count moved over 20% (split, merger), free cash flow is negative, or the company reports in another currency.

Valuation

What we estimate it's worth, and how it ranks on value vs every stock we cover.

Fair value estimate

No estimate for SDGR: negative free cash flow. We’d rather show nothing than a made-up number.

Risk vs market

How risk vs market is measured

One year of daily returns (Oct 31 to Nov 2, 252 sessions). Beta = how much SDGR moved for each 1% move in the S&P 500 (SPY); 1.0 moves with the market. Volatility is the yearly standard deviation of daily returns. Past behavior, not a forecast.

High

Swings much more than the market, and its own price swings are 5.1× the S&P 500’s.

Beta vs S&P 500
1.76
Volatility
66% vs 13% SPY
Correlation SPY
0.34
Correlation QQQ
0.33

How it ranks

Where SDGR stands vs every one of the 2,467 stocks we cover that has the number. Longer bar = better.

Not in the top quarter on any of these 4 measures

  1. Free cash flow yield−6.5% · free cash flow vs market cap
    Lowest 7%of 1,690
  2. Dividends + buybacks yield0% · cash paid out or used to retire shares, vs market cap
    Lowest 1%of 2,227
  3. Revenue growth, last 12 months+8.9% · vs the 12 months before
    Lowest 48%of 2,184
  4. Operating margin−59% · of sales kept as operating profit
    Lowest 2%of 1,549

From SEC filings and our fair value estimate model. A ranking, not advice.

Valuation details

MV $26.02

How

Market ValueAverage paid since the Aug 5 filing, 62 trading days
$26.02price +1%
Fair value estimaten/a — negative free cash flow
n/a
FCF valueTrailing free cash flow is negative
n/a

Fundamentals

The business itself: sales, profits, cash and debt, from SEC filings.

Bull vs bear

Rule-based from the data on this page, strongest first. Not advice.

Top bullish points 3 of 5

  1. ProfitabilityOperating margin widened to −65.2% in FY2025 from −81.9% in FY2023 (SEC filings).

  2. GrowthSales grew 9% to $259M over the last 12 months vs the 12 months before (SEC filings).

  3. GrowthSales grew 12% a year over the last three fiscal years, above the 11% median for the 271 Health Care companies we cover.

Top bearish points 5 of 5

  1. ValuationFree cash flow is negative (−$130M over the last 12 months), so there’s no cash-flow value under the price.

  2. ProfitabilityLost $54M over the last 12 months (net income, SEC filings).

  3. ProfitabilityReturn on equity fell 36 points in two fiscal years, to -28% in FY2025.

  4. ProfitabilityGross margin narrowed to 55.7% in FY2025 from 64.9% in FY2023 (SEC filings).

  5. QualityDoesn’t pass our quality screen: no positive free cash flow; ROE under 12% and ROIC under 10%.

All fundamentals

FCF yield -6.5% · ROE -16% · Sales +9%

Valuation

P/E
n/aloss over the last 12 months
Price / FCF
n/anegative free cash flow
FCF yield
−6.5%
EV / EBITDA
n/aD&A or debt not tagged in SEC data
Price / sales
7.72×
Price / book
6.08×
Market cap
$2.0Blisted
Enterprise value
n/anot reported in its SEC filings

Growth

Revenue, 12 months
$259M
Sales growth, 12 months
+8.9%vs the 12 months before
Sales growth, 3 yrs
+12.2%/yrfrom FY2022
Diluted EPS, 12 months
−$0.73
EPS growth, last FY
n/afewer than two years of diluted EPS
Net income, 12 months
−$54M
Net income growth
n/anot reported in its SEC filings

Profitability

Gross margin
56.9%
Operating margin
−59.2%
Net margin
−21.0%
FCF margin
−50.3%
Return on equity
−16%
Return on invested capital
n/aoperating income, debt, equity or cash not tagged

Balance sheet

Cash & short-term inv.
$414M
Total debt
n/anot reported in its SEC filings
Net cash
n/acash or debt not tagged in SEC data
Debt / equity
n/adebt or equity not tagged in SEC data
Interest coverage
n/ainterest expense not tagged in SEC data

Cash flow & returns

Free cash flow, 12 months
−$130M
FCF growth, 12 months
n/anot reported in its SEC filings
Dividend yield
0%
Payout ratio
n/anot reported in its SEC filings
Buybacks, 12 months
n/anot reported in its SEC filings
Share count, 1 year
+3.2%diluted shares vs a year ago
Stock-based comp
$39M

Trailing 12 months to Jun 30, 2026; balance sheet at Jun 30, 2026. From Schrodinger’s SEC filings. Sparklines show up to six fiscal years. n/a means we don’t hold that number, with the reason. How each is computed.

The business

FCF $-0.1B · Sales +8%
  • Free cash flow, 12 months−$0.1B
  • Free-cash-flow yield-6.5%
  • Gross margin57%
  • Operating margin−71%
  • Return on equity−16%
  • Sales growth (latest quarter vs year-ago quarter)+8%

Chart & levels

Where the price is vs its key levels and trends.

$20$30Jan ’26AprJulOctMV $26.02
Market ValueDrag across the chart to see any day

Key levels

Every level vs today’s $26.19

  1. 52-wk lowlowest close, 1 year$11.07−57.7%
  2. Market Valueavg paid since Aug 5$26.02−0.6%
  3. PriceMon Nov 2 close$26.19you are here
  4. 52-wk highhighest close, 1 year$32.60+24.5%

Momentum & 52-week range

RSI 50 · 5 days +6.9%
$26.19nowMV
52-wk low $11.07high $32.60
Off 52-wk high−19.7%
5 days+6.9%
vs 50-day avg+4.4%
vs 200-day avg+55.9%
RSI (14), last close50
Market cap$2B

Signals

Reversal signal setups, the public ledger and the next earnings date.

Setup & signals

No setup armed

All setups

No setup armed, so there’s no trigger or stop to track yet. Reversal signal rules only run on companies that pass our quality screen.

Next report

Nov 4

Calendar

  • DateWed Nov 4, after the close
  • Consensus EPS($0.65)
  • Year-ago EPS($0.45)
  • QuarterSep/2026

From Nasdaq’s earnings calendar. A report resets Market Value.

SDGR is outside our quality screen

One text when a published rule fires on one of the 332 quality companies we track: the ticker, the price, the stop and a link to the numbers. Nothing else.

By joining you agree we can text or email you about QualityDip. Message and data rates may apply. Reply STOP anytime. Not advice.

Voices & buzz

Who is talking about it, and how it compares with peers.

Who’s talking about it

Notable investors, executives, analysts and public figures on Schrodinger in the last 48 hours. Headlines as published, each linked. Their words, not ours.

No notable mentions in the last 48 hours. Checked Nov 3, 5:14 PM ET.

Compare with peers

Closest in size in Pharmaceuticals

Information only, not investment advice. Fair value estimates and talking points are rule-based model output from public data and can be wrong; stop levels are reference points, not orders. How every number is computed.